I agree with the above posts on the Pandora bracelets. There are so many neat charms - and you can add to it for multiple occasions.
I'm not sure where you live, but I recently paid to have glamour shots taken - hair, makeup, outfits, everything. I'd been feeling down for a long time and it was just the thing to lift my spirits.
Is there a hobby she has always wanted to try - photography, painting, etc? You can see if any local schools are offering classes on something that interests her.
Everyone is different and you know her more than anyone. Hope you are able to find something